อ.ภญ.ดร.พิชชาภา ลินแสนกาศ

Pichchapa Linsaenkart

Pharm.D., Ph.D.

อาจารย์ประจำภาควิชาเภสัชวิทยา

Department
Email

pichchapa.l@chula.ac.th

My research focuses on cellular senescence and senotherapeutic approaches, including senolytics and senomorphics. My expertise includes skin cell biology, particularly melanocyte biology, and the development of 3D human skin equivalent models. My current research centers on the development of pigmented 3D skin models and disease-relevant skin models for investigating skin aging and chronic skin disorders. More recently, I have expanded my research into oral biology, with a particular focus on gingival and periodontal ligament cellular senescence and the development of 3D oral tissue models. I also have experience in formulation development and the evaluation of the biological activities of natural compounds. I welcome opportunities for research collaboration. If our research interests align or you would like to discuss potential collaborations, please feel free to contact me at pichchapa.l@chula.ac.th.

Research Profile
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คุณวุฒิ

ปรัชญาดุษฎีบัณฑิต (Ph.D.)

มหาวิทยาลัยเชียงใหม่

พ.ศ. 2568

เภสัชศาสตร์บัณฑิต (Pharm.D.)

มหาวิทยาลัยเชียงใหม่

พ.ศ. 2564

ผลงานทางวิชาการ

งานวิจัย

ก. บทความวิจัยในวารสาร

  1. Muangsanguan A, Ruksiriwanich W, Linsaenkart P, Tangjaidee P, Sringarm K, Arjin C, Rachtanapun P, Sommano SR, Chaisu K, Satsook A, Castagnini JM. Germination Enhances Phytochemical Profiles of Perilla Seeds and Promotes Hair Growth via 5α-Reductase Inhibition and Growth Factor Pathways. Biology. 2025 Jul 20;14(7):889.
  2. Linsaenkart P, Yooin W, Jiranusornkul S, Sringarm K, Arjin C, Rachtanapun P, Jantanasakulwong K, Castagnini JM, Ruksiriwanich W. Valorization of hom thong banana peel (Musa sp., aaa group) as an anti-melanogenic agent through inhibition of pigmentary genes and molecular docking study. International Journal of Molecular Sciences. 2024 Dec 8;25(23):13202.
  3. Muangsanguan A, Ruksiriwanich W, Linsaenkart P, Jantrawut P, Rachtanapun P, Jantanasakulwong K, Sommano SR, Sringarm K, Arjin C, Sainakham M, Castagnini JM. Synergistic phytochemical and pharmacological actions of Hair RiseTM microemulsion: A novel herbal formulation for androgenetic alopecia and hair growth stimulation. Plants. 2024 Oct 6;13(19):2802.
  4. Linsaenkart P, Ruksiriwanich W, Sringarm K, Arjin C, Rachtanapun P, Chittasupho C, Castagnini JM, Chutoprapat R, Mueller A, Boonpisuttinant K. Anti-melanogenic potential of Malabar spinach (Basella alba) in human melanoma cells with oxidative stress suppression and anti-inflammatory activities. Foods. 2024 Sep 18;13(18):2943.
  5. Linsaenkart P, Ruksiriwanich W, Muangsanguan A, Sommano SR, Sringarm K, Arjin C, Rachtanapun P, Jantanasakulwong K, Castagnini JM, Chutoprapat R, Boonpisuttinant K. Antioxidant, anti-inflammation, and melanogenesis inhibition of Sang 5 CMU rice (Oryza sativa) byproduct for cosmetic applications. Plants. 2024 Jun 28;13(13):1795.
  6. Muangsanguan A, Linsaenkart P, Chaitep T, Sangta J, Sommano SR, Sringarm K, Arjin C, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Castagnini JM. Hair growth promotion and anti-hair loss effects of by-products arabica coffee pulp extracts using supercritical fluid extraction. Foods. 2023 Nov 13;12(22):4116.
  7. Ruksiriwanich W, Linsaenkart P, Muangsanguan A, Sringarm K, Jantrawut P, Arjin C, Sommano SR, Phimolsiripol Y, Barba FJ. Wound healing effect of supercritical carbon dioxide Datura metel L. leaves extracts: An in vitro study of anti-Inflammation, cell migration, MMP-2 Inhibition, and the modulation of the Sonic Hedgehog pathway in human fibroblasts. Plants. 2023 Jul 4;12(13):2546.
  8. Khantham C, Ruksiriwanich W, Chaitep T, Linsaenkart P, Muangsanguan A, Guzmán-Jiménez A, Cerván-Martín M, Bossini-Castillo L, Gonzalez-Muñoz S, Palomino-Morales RJ, Leetrakool N. Sex-specific association of SELL gene polymorphisms with pattern hair loss in the Thai population: A candidate gene association study and in silico functional characterization. Journal of Dermatological Science. 2023 Feb 1;109(2):102-5.
  9. Linsaenkart P, Ruksiriwanich W, Jantrawut P, Chittasupho C, Rachtanapun P, Jantanasakulwong K, Sommano SR, Prom-U-Thai C, Jamjod S, Arjin C, Sringarm K. Natural melanogenesis inhibitor, antioxidant, and collagen biosynthesis stimulator of phytochemicals in rice bran and husk extracts from purple glutinous rice (Oryza sativa L. cv. Pieisu 1 CMU) for cosmetic application. Plants. 2023 Feb 20;12(4):970.
  10. Ruksiriwanich W, Linsaenkart P, Khantham C, Muangsanguan A, Sringarm K, Jantrawut P, Prom-U-Thai C, Jamjod S, Yamuangmorn S, Arjin C, Rachtanapun P. Regulatory effects of thai rice by-product extracts from Oryza sativa L. cv. Bue Bang 3 CMU and Bue Bang 4 CMU on melanin production, nitric oxide secretion, and steroid 5α-reductase inhibition. Plants. 2023 Feb 2;12(3):653.
  11. Ruksiriwanich W, Khantham C, Linsaenkart P, Chaitep T, Jantrawut P, Chittasupho C, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Sommano SR, Arjin C. In vitro and in vivo regulation of SRD5A mRNA expression of supercritical carbon dioxide extract from Asparagus racemosus Willd. root as anti-sebum and pore-minimizing active ingredients. Molecules. 2022 Feb 24;27(5):1535.
  12. Khantham C, Linsaenkart P, Chaitep T, Jantrawut P, Chittasupho C, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Sommano SR, Prom-U-Thai C, Jamjod S. Antioxidation, anti-inflammation, and regulation of SRD5A gene expression of Oryza sativa cv. Bue Bang 3 CMU husk and bran extracts as androgenetic alopecia molecular treatment substances. Plants. 2022 Jan 26;11(3):330.
  13. Ruksiriwanich W, Khantham C, Linsaenkart P, Chaitep T, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Režek Jambrak A, Nazir Y, Yooin W, Sommano SR. Anti-inflammation of bioactive compounds from ethanolic extracts of edible bamboo mushroom (Dictyophora indusiata) as functional health promoting food ingredients. International Journal of Food Science and Technology. 2022 Jan;57(1):110-22.
  14. Nazir Y, Linsaenkart P, Khantham C, Chaitep T, Jantrawut P, Chittasupho C, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Sommano SR, Tocharus J. High efficiency in vitro wound healing of Dictyophora indusiata extracts via anti-Inflammatory and collagen stimulating (MMP-2 inhibition) mechanisms. Journal of Fungi. 2021 Dec 20;7(12):1100.
  15. Ruksiriwanich W, Khantham C, Linsaenkart P, Jantrawut P, Rajchasom S. Optimization of placenta extraction for wound healing activity. Chiang Mai J. Sci. 2019 Sep 1;46:946-59.
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